PROVENGE Treatment Scheduling

Facilitating Treatment Initiation

Dendreon ON Call scheduling coordinators arrange a patient’s full course of therapy and make reminder calls, as well as expertly handle product logistics.

Support Throughout the Treatment Process

A Dendreon ON Call scheduling coordinator can help:

Coordinate the preferences of your practice, your patient, and the apheresis center to schedule the 6 appointments
Make reminder calls to patients before each apheresis appointment

Track Patient Status Online

Conveniently track your patient’s treatment progress online, and communicate with case managers, through the Dendreon ON Call secure Provider Portal.

Dendreon ON Call: Register Your Practice | Sign In

Practice Resources

PROVENGE Patient Enrollment Form:

Dendreon ON Call:

Patient Resources

Starting PROVENGE Patient Brochure:

IMPORTANT SAFETY INFORMATION

Acute Infusion Reactions: Acute infusion reactions (reported within 1 day of infusion) may occur and include nausea, vomiting, fatigue, fever, rigor or chills, respiratory events (dyspnea, hypoxia, and bronchospasm), syncope, hypotension, hypertension, and tachycardia.

Thromboembolic Events: Thromboembolic events, including deep venous thrombosis and pulmonary embolism, can occur following infusion of PROVENGE. The clinical significance and causal relationship are uncertain. Most patients had multiple risk factors for these events. PROVENGE should be used with caution in patients with risk factors for thromboembolic events.

Vascular Disorders: Cerebrovascular events (hemorrhagic/ischemic strokes and transient ischemic attacks) and cardiovascular disorders (myocardial infarctions) have been reported following infusion of PROVENGE. The clinical significance and causal relationship are uncertain. Most patients had multiple risk factors for these events.

Handling Precautions: PROVENGE is not tested for transmissible infectious diseases.

Concomitant Chemotherapy or Immunosuppressive Therapy: Chemotherapy or immunosuppressive agents (such as systemic corticosteroids) given concurrently with the leukapheresis procedure or

PROVENGE has not been studied. Concurrent use of immune-suppressive agents may alter the efficacy and/or safety of PROVENGE.

Adverse Reactions: The most common adverse reactions reported in clinical trials (≥ 15% of patients receiving PROVENGE) were chills, fatigue, fever, back pain, nausea, joint ache, and headache.